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</a> The one-time "Sexiest Man Alive" may be as well known for his political activism as he is for his movies -- but he hasn't turned his back on Hollywood just yet, and will next be seen opposite Martin Sheen and Topher Grace in the upcoming thriller "The Double."
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</a> Although many underlying causes can contribute to kidney disease, diabetes and hypertension are by far the most common ones. "Seventy percent of patients in the U.S. [who] need dialysis [is] due to diabetes or hypertension,但ﾂﾂ� says Uribarri. 但ﾂﾂ廩igh blood glucose produces inflammation that induces scar tissue, which decreases the amount of healthy tissue in the kidney, reducing its ability to filter the blood; high blood pressure eventually also destroys the kidneys, but through different mechanisms.但ﾂﾂ�
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